Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | BACE1 | P56817 | 2/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27318211 | 1.00 | HTT (0.50) | HTTLMNAKMT2AFFAR2MAPT | |
| SCHEMBL27320005 | 0.91 | HTT (0.60) | HTTLMNAKMT2AFFAR2MAPT | |
| SCHEMBL27333980 | 0.86 | GLS (0.52) | HTTLMNAKMT2AFFAR2MAPT | |
| SCHEMBL1691027 | 0.81 | MAPT (0.55) | HTTMAPTPOLBGAARAB9A | |
| SCHEMBL27321055 | 0.81 | GAA (0.49) | HTTFFAR2MAPTPOLBGAA | |
| SCHEMBL11188449 | 0.81 | FFAR2 (0.44) | LMNAKMT2AFFAR2POLBGAA | |
| SCHEMBL11188438 | 0.81 | FFAR2 (0.44) | LMNAKMT2AFFAR2POLBGAA | |
| SCHEMBL11288091 | 0.81 | FFAR2 (0.44) | LMNAKMT2AFFAR2POLBGAA | |
| SCHEMBL8923179 | 0.80 | HTT (0.52) | HTTLMNAKMT2AFFAR2MAPT | |
| SCHEMBL27323009 | 0.76 | MAPK1 (0.62) | LMNAMAPTPOLBRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663162-A | BACTERICIDES AND ANTIBIOTICS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-09-02 | — | — | US | disclosed |