Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 18/20 | 0.44 |
| ▸ | DRD2 | P14416 | 16/20 | 0.44 |
| ▸ | HTR2A | P28223 | 15/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | HTR1D | P28221 | 2/20 | 0.39 |
| ▸ | HTR1B | P28222 | 2/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8917721 | 0.90 | HTR1A (0.40) | HTR1ADRD2HTR2ASLC6A4HTR1D | |
| SCHEMBL8917224 | 0.86 | HTR1A (0.42) | HTR1ADRD2HTR2ASLC6A4HTR1D | |
| SCHEMBL8919069 | 0.86 | HTR1A (0.44) | HTR1ADRD2HTR2ASLC6A4HTR1D | |
| SCHEMBL8919178 | 0.83 | HTR1A (0.41) | HTR1ADRD2HTR2ASLC6A4HTR1D | |
| SCHEMBL8916899 | 0.83 | HTR1A (0.41) | HTR1ADRD2HTR2ASLC6A4HTR1D | |
| SCHEMBL8918317 | 0.81 | HTR1A (0.46) | HTR1ADRD2HTR2ASLC6A4 | |
| SCHEMBL8920638 | 0.80 | TSHR (0.38) | HTR1ADRD2HTR2ASLC6A4HTR1D | |
| SCHEMBL8918749 | 0.80 | HTR1A (0.37) | HTR1ADRD2HTR2ASLC6A4HTR1D | |
| SCHEMBL8917225 | 0.79 | HTR1A (0.39) | HTR1ADRD2HTR2ASLC6A4HTR1D | |
| SCHEMBL8916474 | 0.78 | HTR1A (0.41) | HTR1ADRD2HTR2ASLC6A4HTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |