Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 18/20 | 0.37 |
| ▸ | DRD2 | P14416 | 8/20 | 0.37 |
| ▸ | HTR2A | P28223 | 7/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.37 |
| ▸ | HTR1D | P28221 | 8/20 | 0.37 |
| ▸ | HTR1B | P28222 | 8/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8920638 | 0.93 | TSHR (0.38) | HTR1ADRD2HTR2AMEN1TSHR | |
| SCHEMBL8919178 | 0.90 | HTR1A (0.41) | HTR1ADRD2HTR2ASLC6A4HTR1D | |
| SCHEMBL8917179 | 0.84 | DRD2 (0.40) | HTR1ADRD2HTR2AMEN1TSHR | |
| SCHEMBL8916899 | 0.84 | HTR1A (0.41) | HTR1ADRD2HTR2ASLC6A4HTR1D | |
| SCHEMBL8916916 | 0.84 | HTR2A (0.42) | HTR1ADRD2HTR2ADRD4 | |
| SCHEMBL8917721 | 0.83 | HTR1A (0.40) | HTR1ADRD2HTR2AMEN1TSHR | |
| SCHEMBL8917225 | 0.83 | HTR1A (0.39) | HTR1ADRD2HTR2AMEN1TSHR | |
| SCHEMBL8916905 | 0.82 | MAPT (0.48) | HTR1ADRD2HTR2ASLC6A4 | |
| SCHEMBL8917224 | 0.80 | HTR1A (0.42) | HTR1ADRD2HTR2ASLC6A4HTR1D | |
| SCHEMBL8919037 | 0.80 | HTR1A (0.44) | HTR1ADRD2HTR2ASLC6A4HTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | claimed |
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |