Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.85 |
| ▸ | USP2 | O75604 | 1/20 | 0.85 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.75 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.69 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.66 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.66 |
| ▸ | ACHE | P22303 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL243236 | 1.00 | HPGD (1.00) | HPGDALDH1A1USP2MAPK1LMNA | |
| SCHEMBL1927946 | 1.00 | HPGD (1.00) | HPGDALDH1A1USP2MAPK1LMNA | |
| SCHEMBL27929296 | 1.00 | HPGD (1.00) | HPGDALDH1A1USP2MAPK1LMNA | |
| SCHEMBL436090 | 1.00 | HPGD (1.00) | HPGDALDH1A1USP2MAPK1LMNA | |
| Bicarbonate SCHEMBL1582960 | 0.98 | HPGD (0.96) | HPGDALDH1A1USP2MAPK1LMNA | |
| Hydrochloric Acid SCHEMBL9209631 | 0.98 | HPGD (0.96) | HPGDALDH1A1USP2MAPK1LMNA | |
| SCHEMBL254870 | 0.98 | HPGD (0.96) | HPGDALDH1A1USP2MAPK1LMNA | |
| SCHEMBL18228404 | 0.98 | HPGD (0.96) | HPGDALDH1A1USP2MAPK1LMNA | |
| SCHEMBL1263133 | 0.93 | HPGD (0.88) | HPGDALDH1A1USP2MAPK1LMNA | |
| SCHEMBL2614241 | 0.91 | HPGD (0.84) | HPGDALDH1A1USP2MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5648521-A | DECYCLIZATION, OXIDATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-07-15 | — | — | US | disclosed |