Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.85 |
| ▸ | USP2 | O75604 | 1/20 | 0.85 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.75 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.69 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.66 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.66 |
| ▸ | ACHE | P22303 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1927946 | 1.00 | HPGD (1.00) | HPGDALDH1A1USP2MAPK1LMNA | |
| SCHEMBL27929296 | 1.00 | HPGD (1.00) | HPGDALDH1A1USP2MAPK1LMNA | |
| SCHEMBL8919062 | 1.00 | HPGD (1.00) | HPGDALDH1A1USP2MAPK1LMNA | |
| SCHEMBL436090 | 1.00 | HPGD (1.00) | HPGDALDH1A1USP2MAPK1LMNA | |
| Bicarbonate SCHEMBL1582960 | 0.98 | HPGD (0.96) | HPGDALDH1A1USP2MAPK1LMNA | |
| Hydrochloric Acid SCHEMBL9209631 | 0.98 | HPGD (0.96) | HPGDALDH1A1USP2MAPK1LMNA | |
| SCHEMBL254870 | 0.98 | HPGD (0.96) | HPGDALDH1A1USP2MAPK1LMNA | |
| SCHEMBL18228404 | 0.98 | HPGD (0.96) | HPGDALDH1A1USP2MAPK1LMNA | |
| SCHEMBL1263133 | 0.93 | HPGD (0.88) | HPGDALDH1A1USP2MAPK1LMNA | |
| SCHEMBL2614241 | 0.91 | HPGD (0.84) | HPGDALDH1A1USP2MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 944 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122010701-A | Carbonyl compound and preparation method thereof | 南京工业大学 | 2026-05-12 | — | — | CN | claimed |
| CN-120058701-A | Thioether structure-containing targeted PHGDH active molecular probe, preparation method and application thereof | 中国药科大学 | 2025-05-30 | — | — | CN | claimed |
| CN-119874605-A | Benzoyl piperidinyl piperidine derivatives, preparation method and application thereof | 南通大学 | 2025-04-25 | — | — | CN | claimed |
| CN-118666735-A | Synthesis method of (R) -2-ethylpiperidine-2-formic acid | 吉尔多肽生物制药(大连市)有限公司 | 2024-09-20 | — | — | CN | claimed |
| US-20240300931-A1 | Composition and Methods for Treating Attention Deficit Disorders | LIPPA ARNOLD STAN (US) | 2024-09-12 | — | — | US | claimed |
| US-20240100023-A1 | Compositions and Methods For Treating Spinal Cord Injuries | LIPPA ARNOLD S (US) | 2024-03-28 | — | — | US | claimed |
| US-20230373982-A1 | Compositions And Methods For Treating Attention Deficit Disorders | LIPPA ARNOLD STAN (US) | 2023-11-23 | — | — | US | claimed |
| US-11787785-B2 | Pyrazolopyridine derivatives and uses thereof | NOVARTIS AG (CH) | 2023-10-17 | — | — | US | claimed |
| CN-116217352-A | Method for preparing cannabigerol and analogues thereof | 上海中医药大学 | 2023-06-06 | — | — | CN | claimed |
| US-20230129330-A1 | Compositions And Methods For Treating Attention Deficit Disorders | LIPPA ARNOLD STAN (US) | 2023-04-27 | — | — | US | claimed |
| EP-0377357-A1 | Process for the condensation of at least one epoxide on at least one cyclic anhyhride in the presence of a titanium-based catalyst | Institut Français du Pétrole (FR) | 1990-07-11 | — | — | EP | claimed |
| US-4843077-A | Isoquinoline derivatives having renal vasodilating properties and/or cardiotonic properties and/or phosphodiesterase inhibiting properties | ORTHO PHARMACEUTICAL CORPORATION (US) | 1989-06-27 | — | — | US | claimed |
| EP-0202164-B1 | (BENZOYL-4-PIPERIDINO)-2-PHENYL-1-ALKANOL DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICINES | SYNTHELABO (FR) | 1989-02-08 | — | — | EP | claimed |
| EP-0080104-B1 | 3-(4-PIPERIDYL)-1,2-BENZISOXAZOLES, PROCESS FOR THE PREPARATION THEREOF, AND A PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1988-12-14 | — | — | EP | claimed |
| EP-0135349-B1 | CONDENSED SEVEN-MEMBERED RING COMPOUNDS AND THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1988-11-02 | — | — | EP | claimed |
| EP-0202164-A1 | (Benzoyl-4-piperidino)-2-phenyl-1-alkanol derivatives, their preparation and their use as medicines | SYNTHELABO (FR) | 1986-11-20 | — | — | EP | claimed |
| EP-0080104-A2 | 3-(4-Piperidyl)-1,2-benzisoxazoles, process for the preparation thereof, and a pharmaceutical composition comprising the same | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1983-06-01 | — | — | EP | claimed |
| EP-0019411-B1 | 1-PHENYL-2-AMINOETHANOL DERIVATIVES, PROCESSES FOR THEIR MANUFACTURE AND PHARMACEUTICAL COMPOSITIONS THEREOF | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-12-22 | — | — | EP | claimed |
| US-4199021-A | Thermal energy storage apparatus | JOHNSON CONTROLS, INC. (US) | 1980-04-22 | — | — | US | claimed |
| US-4072712-A | FROM ISOCYANATES, CATALYSIS | BAYER AKTIENGESELLSCHAFT (DT) | 1978-02-07 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11787785-B2 | Pyrazolopyridine derivatives and uses thereof | HBZ, ZFX, WIZ | HPGD 1030/4885ALDH1A1 1243/4885USP2 4303/4885 |
| US-20240100023-A1 | Compositions and Methods For Treating Spinal Cord Injuries | CHAT, NTRK2, GMFG | HPGD 2429/4885ALDH1A1 581/4885USP2 2658/4885 |
| US-20230129330-A1 | Compositions And Methods For Treating Attention Deficit Disorders | GRIN2A, GRIN2C, GRM2 | HPGD 1967/4885ALDH1A1 1104/4885USP2 2702/4885 |
| US-20230373982-A1 | Compositions And Methods For Treating Attention Deficit Disorders | GRIN2A, GRIN2C, GRM2 | HPGD 1967/4885ALDH1A1 1104/4885USP2 2702/4885 |
| US-20240300931-A1 | Composition and Methods for Treating Attention Deficit Disorders | GRIN2A, GRIN2C, NTRK2 | HPGD 2020/4885ALDH1A1 1214/4885USP2 2881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.