Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 8/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8916959 | 0.91 | TP53 (0.39) | TP53THRBMAPTGAAHTR3A | |
| SCHEMBL8917290 | 0.87 | TP53 (0.36) | TP53THRBMAPTGAAHTR3A | |
| SCHEMBL8916431 | 0.85 | TP53 (0.38) | TP53THRBMAPTGAAHTR3A | |
| SCHEMBL8919168 | 0.84 | TP53 (0.49) | TP53THRBMAPTGAAHTR1A | |
| SCHEMBL8916994 | 0.84 | HTR2A (0.43) | TP53MAPTGAAHTR1A | |
| SCHEMBL8916598 | 0.82 | TP53 (0.36) | TP53THRBMAPTGAAHTR3A | |
| SCHEMBL8918541 | 0.82 | TP53 (0.38) | TP53THRBMAPTGAAHTR3A | |
| SCHEMBL8915765 | 0.82 | MAPT (0.38) | TP53THRBMAPTHTR3APOLB | |
| SCHEMBL8916455 | 0.82 | MAPT (0.44) | TP53THRBMAPTPOLB | |
| SCHEMBL8917325 | 0.79 | MAPT (0.40) | TP53THRBMAPTGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |