Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.40 |
| ▸ | TP53 | P04637 | 7/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8916943 | 0.88 | TP53 (0.38) | MAPTTP53POLBMCHR1DRD2 | |
| SCHEMBL8916433 | 0.86 | TP53 (0.40) | MAPTTP53POLBMCHR1DRD2 | |
| SCHEMBL8916959 | 0.86 | TP53 (0.39) | MAPTTP53POLBDRD2GAA | |
| SCHEMBL8919123 | 0.84 | DRD2 (0.39) | MAPTTP53POLBMCHR1DRD2 | |
| SCHEMBL8915726 | 0.84 | CTSS (0.40) | MAPTTP53POLBMCHR1DRD2 | |
| SCHEMBL8916461 | 0.83 | TP53 (0.40) | MAPTTP53POLBMCHR1DRD2 | |
| Hydrochloric Acid SCHEMBL8916568 | 0.82 | TP53 (0.39) | MAPTTP53POLBMCHR1DRD2 | |
| SCHEMBL8916709 | 0.82 | CTSS (0.49) | MAPTTP53POLBMCHR1DRD2 | |
| Hydrochloric Acid SCHEMBL8920486 | 0.81 | CTSS (0.48) | MAPTTP53POLBMCHR1DRD2 | |
| SCHEMBL8917705 | 0.80 | DRD2 (0.52) | MAPTTP53POLBMCHR1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |