Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 3/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8919168 | 0.94 | TP53 (0.49) | HTR2ADRD4TP53ADRA1AMAPT | |
| SCHEMBL8915765 | 0.91 | MAPT (0.38) | HTR2ADRD4TP53MAPTMEN1 | |
| SCHEMBL8916455 | 0.86 | MAPT (0.44) | TP53MAPTMEN1KMT2ABAZ2B | |
| SCHEMBL8916709 | 0.86 | CTSS (0.49) | TP53MAPTGAACTSSDRD2 | |
| Hydrochloric Acid SCHEMBL8920486 | 0.85 | CTSS (0.48) | TP53MAPTGAACTSSDRD2 | |
| SCHEMBL8916688 | 0.85 | MAPT (0.37) | HTR2ATP53MAPTGAACTSS | |
| SCHEMBL8917290 | 0.84 | TP53 (0.36) | TP53MAPTGAAHTR1A | |
| SCHEMBL8919144 | 0.84 | TP53 (0.38) | TP53MAPTGAAHTR1A | |
| SCHEMBL8918059 | 0.83 | MAPT (0.37) | TP53MAPTGAAMEN1KMT2A | |
| SCHEMBL8916959 | 0.82 | TP53 (0.39) | HTR2ATP53ADRA1AMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |