Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.43 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | DRD1 | P21728 | 3/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | BPTF | Q12830 | 1/20 | 0.35 |
| ▸ | BAZ2B | Q9UIF8 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.34 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.34 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.34 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.34 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8918025 | 0.89 | HTR1A (0.43) | HTR1ADRD2DRD1NOTUMMCHR1 | |
| SCHEMBL8916613 | 0.86 | NOTUM (0.43) | DRD2DRD1NOTUMMCHR1HDAC6 | |
| SCHEMBL8918612 | 0.84 | HTR1A (0.40) | HTR1ADRD2DRD1NOTUMMCHR1 | |
| SCHEMBL8917672 | 0.77 | MCHR1 (0.62) | NOTUMMCHR1HDAC6HRH3F2 | |
| SCHEMBL8916750 | 0.76 | NOTUM (0.43) | NOTUMMCHR1HDAC6BPTFBAZ2B | |
| SCHEMBL21411146 | 0.76 | HDAC6 (0.49) | NOTUMMCHR1HDAC6BPTFBAZ2B | |
| SCHEMBL3445744 | 0.75 | MCHR1 (0.41) | NOTUMMCHR1HDAC6HRH3POLB | |
| SCHEMBL3555661 | 0.74 | NOTUM (0.47) | NOTUMMCHR1HDAC6BPTFBAZ2B | |
| SCHEMBL8916698 | 0.72 | BPTF (0.39) | NOTUMBPTFBAZ2BPOLBGRM5 | |
| SCHEMBL17385378 | 0.72 | PRKDC (0.45) | NOTUMMCHR1HDAC6GRM5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0596125-A1 | CONDENSED THIOPHENE COMPOUND AND PHARMACEUTICAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-05-11 | — | — | EP | disclosed |