Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | BPTF | Q12830 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.34 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.34 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.34 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.34 |
| ▸ | BAZ2B | Q9UIF8 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8916750 | 0.89 | NOTUM (0.43) | NOTUMHDAC6MCHR1GRM5BPTF | |
| SCHEMBL8919325 | 0.86 | HTR1A (0.43) | NOTUMHDAC6MCHR1GRM5BPTF | |
| SCHEMBL21411146 | 0.79 | HDAC6 (0.49) | NOTUMHDAC6MCHR1GRM5BPTF | |
| SCHEMBL8918025 | 0.76 | HTR1A (0.43) | NOTUMHDAC6MCHR1GRM5BPTF | |
| SCHEMBL3445744 | 0.75 | MCHR1 (0.41) | NOTUMHDAC6MCHR1HRH3POLB | |
| SCHEMBL17385378 | 0.75 | PRKDC (0.45) | NOTUMHDAC6MCHR1GRM5ALDH1A1 | |
| SCHEMBL3555661 | 0.74 | NOTUM (0.47) | NOTUMHDAC6MCHR1GRM5BPTF | |
| SCHEMBL3441449 | 0.71 | HDAC6 (0.42) | HDAC6MCHR1POLBF2TPSAB1 | |
| SCHEMBL8680457 | 0.71 | ALDH1A1 (0.45) | NOTUMHDAC6MCHR1BPTFPOLB | |
| SCHEMBL8918612 | 0.71 | HTR1A (0.40) | NOTUMHDAC6MCHR1GRM5BPTF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |