Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.44 |
| ▸ | KLK7 | P49862 | 1/20 | 0.42 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | PREP | P48147 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | STAT6 | P42226 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8917522 | 0.91 | ACE2 (0.42) | ACE2KLK7ACEMEN1KMT2A | |
| SCHEMBL3045671 | 0.83 | FKBP1A (0.45) | KLK7FKBP1AACEMEN1KMT2A | |
| SCHEMBL3045668 | 0.83 | FKBP1A (0.45) | KLK7FKBP1AACEMEN1KMT2A | |
| SCHEMBL3046635 | 0.82 | FKBP1A (0.45) | KLK7FKBP1AMEN1KMT2ASTAT6 | |
| SCHEMBL3046636 | 0.82 | FKBP1A (0.45) | KLK7FKBP1AMEN1KMT2ASTAT6 | |
| SCHEMBL3046386 | 0.81 | STAT6 (0.50) | KLK7FKBP1AACEMEN1KMT2A | |
| SCHEMBL3046383 | 0.81 | STAT6 (0.50) | KLK7FKBP1AACEMEN1KMT2A | |
| SCHEMBL3051711 | 0.81 | KLK7 (0.47) | KLK7ACEMEN1KMT2AMAPT | |
| SCHEMBL3051710 | 0.81 | KLK7 (0.47) | KLK7ACEMEN1KMT2AMAPT | |
| SCHEMBL7333711 | 0.75 | KLK7 (0.58) | KLK7CTRB1FKBP1AACEPREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686565-A | ANTIINFLAMMATORY AGENTS | SCIOS INC. (US) | 1997-11-11 | — | — | US | disclosed |
| US-5552383-A | ANALGESIC, ANTIINFLAMMATORY FOR WOUNDS | SCIOS NOVA INC. (US) | 1996-09-03 | — | — | US | disclosed |