Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 13/20 | 0.79 |
| ▸ | MEN1 | O00255 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8331178 | 0.98 | HSD11B1 (0.79) | HSD11B1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL3129900 | 0.89 | HSD11B1 (1.00) | HSD11B1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL8327261 | 0.87 | SMN1; SMN2 (0.74) | HSD11B1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL6896465 | 0.85 | MEN1 (1.00) | HSD11B1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL16507207 | 0.85 | MEN1 (0.93) | HSD11B1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL14289421 | 0.81 | HSD11B1 (0.79) | HSD11B1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL4630666 | 0.81 | HSD11B1 (0.79) | HSD11B1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL6543280 | 0.80 | HSD11B1 (0.79) | HSD11B1MEN1KMT2AALDH1A1LMNA | |
| Water SCHEMBL6544000 | 0.80 | HSD11B1 (0.77) | HSD11B1MEN1KMT2AALDH1A1LMNA | |
| Water SCHEMBL6544001 | 0.80 | HSD11B1 (0.77) | HSD11B1MEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808303-A1 | 5-(4-SUBST.-PIPERIDINYL-1)-3-ARYL-PENTANOIC ACID DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONIST | ZENECA LIMITED (GB) | 1997-11-26 | — | — | EP | disclosed |
| WO-1996024582-A1 | 5-(4-SUBST.-PIPERIDINYL-1)-3-ARYL-PENTANOIC ACID DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONIST | ZENECA LIMITED (GB) | 1996-08-15 | — | — | WO | disclosed |