Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MLYCD | O95822 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8626795 | 0.83 | TSHR (0.44) | TSHRSMN1; SMN2MAPTALDH1A1GLA | |
| SCHEMBL5812624 | 0.77 | TSHR (0.51) | TSHRSMN1; SMN2MAPTALDH1A1GLA | |
| Hydrochloric Acid SCHEMBL5967307 | 0.76 | MLYCD (0.47) | TSHRSMN1; SMN2ALDH1A1GLASLC15A1 | |
| SCHEMBL5966898 | 0.74 | SMN1; SMN2 (0.40) | TSHRSMN1; SMN2ALDH1A1GLASLC15A1 | |
| SCHEMBL28110901 | 0.74 | MLYCD (0.46) | TSHRALDH1A1GLAMLYCD | |
| SCHEMBL5967205 | 0.72 | MLYCD (0.50) | TSHRSMN1; SMN2ALDH1A1GLAKDM4E | |
| Hydrochloric Acid SCHEMBL5966878 | 0.71 | MLYCD (0.44) | TSHRSMN1; SMN2ALDH1A1GLAKDM4E | |
| Hydrochloric Acid SCHEMBL5967060 | 0.70 | MLYCD (0.49) | TSHRSMN1; SMN2ALDH1A1GLAKDM4E | |
| SCHEMBL7443874 | 0.70 | TSHR (0.51) | TSHRSMN1; SMN2MAPTALDH1A1SLC15A1 | |
| SCHEMBL28156312 | 0.70 | TSHR (0.50) | TSHRSMN1; SMN2MAPTALDH1A1CACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658935-A | USEFUL AS INHIBITORS OF THROMBOCYTE AGGREGATION, THE METASTASIS OF CARCINOMA CELLS AND THE BINDING OF OSTEOCLASTS ON BONE SURFACES | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-08-19 | — | — | US | disclosed |