Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8919576 | 0.83 | TSHR (0.41) | TSHRSMN1; SMN2MAPTALDH1A1GLA | |
| SCHEMBL8957381 | 0.80 | MEN1 (0.40) | TSHRSMN1; SMN2ALDH1A1GLAMLYCD | |
| SCHEMBL5812624 | 0.80 | TSHR (0.51) | TSHRSMN1; SMN2MAPTALDH1A1GLA | |
| SCHEMBL1822076 | 0.80 | MLYCD (0.44) | TSHRSMN1; SMN2ALDH1A1GLAMLYCD | |
| Hydrochloric Acid SCHEMBL8627165 | 0.79 | MEN1 (0.39) | TSHRSMN1; SMN2ALDH1A1GLAMLYCD | |
| Hydrochloric Acid SCHEMBL11694104 | 0.78 | MLYCD (0.43) | TSHRSMN1; SMN2ALDH1A1GLAMLYCD | |
| SCHEMBL11047128 | 0.78 | ALDH1A1 (0.44) | TSHRSMN1; SMN2ALDH1A1GLAMLYCD | |
| Hydrochloric Acid SCHEMBL5967108 | 0.77 | MLYCD (0.45) | TSHRALDH1A1GLAMLYCD | |
| Trifluoroacetic Acid SCHEMBL8626777 | 0.77 | MLYCD (0.48) | MLYCD | |
| SCHEMBL6930491 | 0.76 | SMN1; SMN2 (0.39) | TSHRSMN1; SMN2ALDH1A1GLAMLYCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0689549-B1 | NEW UREA DERIVATES, THEIR PREPARATION AND THEIR USE | HOECHST AG (DE) | 1998-06-17 | — | — | EP | disclosed |
| US-5703050-A | INHIBIT PLATELET AGGREGATION, METASTASIS OF CARCINOMA CELLS, OSTEOCLAST BINDING TO BONE SURFACE | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-12-30 | — | — | US | disclosed |
| EP-0689549-A1 | NEW UREA DERIVATES, THEIR PREPARATION AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-01-03 | — | — | EP | disclosed |
| WO-1994022907-A1 | NEW UREA DERIVATES, THEIR PREPARATION AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-10-13 | — | — | WO | disclosed |