Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6304863 | 0.79 | — | — | |
| SCHEMBL15266796 | 0.79 | — | — | |
| SCHEMBL5076862 | 0.78 | — | — | |
| SCHEMBL9619936 | 0.72 | — | — | |
| SCHEMBL44788 | 0.70 | MAOA (0.32) | — | |
| SCHEMBL10544273 | 0.68 | KMT2A (0.36) | — | |
| SCHEMBL262994 | 0.68 | PYGM (0.35) | — | |
| SCHEMBL11346988 | 0.68 | — | — | |
| SCHEMBL6895182 | 0.68 | TSHR (0.32) | — | |
| Formaldehyde SCHEMBL10840621 | 0.67 | MAOA (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693602-A | MIXTURE OF AMYLASE AND PROTEASE | COLGATE-PALMOLIVE CO. (US) | 1997-12-02 | — | — | US | disclosed |
| US-5468411-A | Contains protease and amylase enzymes | COLGATE PALMOLIVE CO. (US) | 1995-11-21 | — | — | US | disclosed |
| US-5423997-A | Stable concentrate containing protease and amylase enzymes | COLGATE PALMOLIVE CO. (US) | 1995-06-13 | — | — | US | disclosed |
| EP-0640684-A1 | Spray dried powdered automatic dishwashing composition containing enzymes | Colgate-Palmolive Company (US) | 1995-03-01 | — | — | EP | disclosed |
| US-5173207-A | Protease enzyme and amylase enzyme, nonionic surfactants, alkali metal silicate | COLGATE-PALMOLIVE COMPANY (US) | 1992-12-22 | — | — | US | disclosed |
| EP-0516553-A2 | Powdered automatic dishwashing composition containing enzymes | Colgate-Palmolive Company (US) | 1992-12-02 | — | — | EP | disclosed |