Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.41 |
| ▸ | RELA | Q04206 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9093005 | 0.85 | SLC6A2 (0.46) | NPC1RAB9AL3MBTL1NOTUMALDH1A1 | |
| SCHEMBL7469639 | 0.73 | NPC1 (1.00) | NPC1RAB9AL3MBTL1NOTUMALDH1A1 | |
| SCHEMBL30659283 | 0.73 | NPC1 (1.00) | NPC1RAB9AL3MBTL1NOTUMALDH1A1 | |
| SCHEMBL19420152 | 0.73 | POLB (0.59) | L3MBTL1ALDH1A1TSHRMAPTMEN1 | |
| SCHEMBL30530526 | 0.72 | MAPT (0.55) | NPC1RAB9AL3MBTL1NOTUMALDH1A1 | |
| SCHEMBL11621424 | 0.72 | SLC6A2 (0.48) | NPC1RAB9AL3MBTL1NOTUMALDH1A1 | |
| SCHEMBL14495647 | 0.71 | NOTUM (0.63) | NPC1RAB9AL3MBTL1NOTUMALDH1A1 | |
| SCHEMBL27668090 | 0.71 | POLB (0.49) | NPC1RAB9ANOTUMALDH1A1TSHR | |
| SCHEMBL9987125 | 0.70 | ALDH1A1 (0.44) | L3MBTL1ALDH1A1KDM4EPOLBKMT2A | |
| SCHEMBL7045087 | 0.70 | NPC1 (0.61) | NPC1RAB9AL3MBTL1NOTUMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691272-A | Carboxylate and heat-sensitive recording material using same | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5559247-A | Carboxylate and heat-sensitive recording material using same | MITSUI TOATSU CHEMICALS, INC. (JP) | 1996-09-24 | — | — | US | disclosed |