Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | P4HB | P07237 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8672898 | 0.81 | OPRM1 (0.54) | KMT2AMEN1ALDH1A1NPSR1OPRM1 | |
| SCHEMBL13653654 | 0.81 | MAPT (0.51) | MAPTKDM4EHPGDALOX15SMN1; SMN2 | |
| SCHEMBL13553399 | 0.81 | KDM4E (0.51) | MAPTKDM4EHPGDALOX15SMN1; SMN2 | |
| SCHEMBL13653662 | 0.79 | KDM4E (0.49) | MAPTKDM4EHPGDALOX15SMN1; SMN2 | |
| SCHEMBL11886645 | 0.79 | KDM4E (0.49) | MAPTKDM4EHPGDALOX15SMN1; SMN2 | |
| SCHEMBL11885437 | 0.78 | MAPT (0.49) | MAPTKDM4EHPGDALOX15SMN1; SMN2 | |
| SCHEMBL11885445 | 0.76 | KDM4E (0.47) | MAPTKDM4EHPGDALOX15SMN1; SMN2 | |
| SCHEMBL20690487 | 0.76 | TACR1 (0.51) | MAPTKDM4EHPGDALOX15SMN1; SMN2 | |
| SCHEMBL4590358 | 0.76 | MAPT (0.50) | MAPTKDM4EHPGDALOX15SMN1; SMN2 | |
| SCHEMBL29700504 | 0.76 | TACR1 (0.51) | MAPTKDM4EHPGDALOX15SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696123-A | ALPHA-PIPERAZINYL BENZYL COMPOUND AS TACHYKININ ANTAGONIST TREATING ASTHMA, BRONCHITIS, SKIN DISORDER, EYE DISEASE, HEADACHE, GASTROINTESTINAL DISORDER | BOEHRINGER INGELHEIM KG (DE) | 1997-12-09 | — | — | US | disclosed |