Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 1/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | UBE2N | P61088 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9242254 | 0.77 | ALDH1A1 (0.42) | LMNAPOLBKDM4ETP53CYP3A4 | |
| Methylhydrazine SCHEMBL10992520 | 0.72 | HSP90AA1 (0.40) | LMNAPOLBKDM4ETP53CYP3A4 | |
| SCHEMBL8070808 | 0.71 | KDM4E (0.39) | LMNAKDM4EMAPTHTT | |
| SCHEMBL7605770 | 0.71 | KDM4E (0.39) | LMNAKDM4EMAPTHTT | |
| SCHEMBL15166980 | 0.70 | KDM4E (0.32) | KDM4E | |
| SCHEMBL9122047 | 0.69 | PDE4A (0.47) | PTGER1PTGER4PTGER3LMNABLM | |
| SCHEMBL8919967 | 0.68 | PTGER4 (0.36) | PTGER1PTGER4PTGER3 | |
| SCHEMBL8017747 | 0.67 | PTGER1 (0.34) | PTGER1PTGER4PTGER3CYP2D6 | |
| SCHEMBL21911678 | 0.67 | ALDH1A1 (0.39) | POLBBLMKDM4ECYP1A2CYP3A4 | |
| SCHEMBL7607451 | 0.66 | ADORA2B (0.33) | LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670507-A | Method for reversing multiple drug resistant phenotype | CELL THERAPEUTICS, INC. (US) | 1997-09-23 | — | — | US | disclosed |