Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.40 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10799781 | 0.89 | SMN1; SMN2 (0.46) | MAPTTDP1MAPK1POLBALDH1A1 | |
| SCHEMBL8923066 | 0.81 | LMNA (0.47) | MAPTTDP1MAPK1POLBALDH1A1 | |
| SCHEMBL1549092 | 0.79 | ABL1 (0.48) | ABL1MAPTTDP1POLBALDH1A1 | |
| SCHEMBL505205 | 0.79 | TDP1 (0.47) | ABL1MAPTTDP1MAPK1POLB | |
| SCHEMBL3856555 | 0.77 | ABL1 (0.54) | ABL1MAPTALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL1116207 | 0.76 | ABL1 (0.54) | ABL1MAPTTDP1POLBALDH1A1 | |
| SCHEMBL8574438 | 0.76 | ABL1 (0.53) | ABL1MAPTPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL2043408 | 0.75 | MEN1 (0.50) | MAPTTDP1MAPK1POLBSMN1; SMN2 | |
| SCHEMBL1800859 | 0.75 | ALDH1A1 (0.51) | MAPTTDP1MAPK1POLBALDH1A1 | |
| SCHEMBL12000739 | 0.75 | TDP1 (0.49) | ABL1MAPTTDP1MAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633379-A | N-METHYLASPARTIC ACID ANTAGONIST | CIBA-GEIGY CORPORATION (US) | 1997-05-27 | — | — | US | disclosed |
| EP-0685466-A1 | 3-Heteroaliphatyle-and 3-hetero-(aryle)-aliphatyle-2(1H)-quinolone derivatives | CIBA-GEIGY AG (CH) | 1995-12-06 | — | — | EP | disclosed |