Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.62 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | DGKA | P23743 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7997856 | 0.97 | TSHR (0.66) | TSHRTHRBHPGDALDH1A1ATM | |
| SCHEMBL15130313 | 0.92 | TSHR (0.74) | TSHRTHRBHPGDALDH1A1ATM | |
| SCHEMBL10963529 | 0.91 | TSHR (0.58) | TSHRTHRBHPGDALDH1A1ATM | |
| SCHEMBL930891 | 0.90 | TSHR (0.77) | TSHRTHRBHPGDALDH1A1TDP1 | |
| SCHEMBL9788553 | 0.90 | TSHR (0.77) | TSHRTHRBHPGDALDH1A1TDP1 | |
| Ethylene SCHEMBL5680057 | 0.90 | THRB (0.55) | TSHRTHRBHPGDALDH1A1TDP1 | |
| SCHEMBL9682225 | 0.88 | TSHR (0.56) | TSHRTHRBHPGDALDH1A1ATM | |
| SCHEMBL10457292 | 0.88 | TSHR (0.63) | TSHRTHRBHPGDALDH1A1ATM | |
| SCHEMBL9696561 | 0.88 | THRB (0.57) | TSHRTHRBHPGDALDH1A1TDP1 | |
| SCHEMBL1952425 | 0.88 | TSHR (0.67) | TSHRTHRBHPGDALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677407-A | TERPOLYMER OF BUTYL METHACRYLATE, ALLYL METHACRYLATE, ETHYLENE GLYCOL DIMETHACRYLATE | AMCOL INTERNATIONAL CORPORATION (US) | 1997-10-14 | — | — | US | claimed |