Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.38 |
| ▸ | CCR3 | P51677 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8918122 | 0.99 | KMT2A (0.45) | KMT2ACYP2C9CYP2C19MAPK14POLB | |
| SCHEMBL8922159 | 0.82 | MEN1 (0.43) | KMT2ACYP2C9CYP2C19MAPK14POLB | |
| Hydrochloric Acid SCHEMBL8920610 | 0.82 | ALDH1A1 (0.45) | KMT2ACYP2C9CYP2C19MAPK14POLB | |
| Hydrochloric Acid SCHEMBL8919801 | 0.82 | MEN1 (0.42) | KMT2ACYP2C9CYP2C19MAPK14POLB | |
| SCHEMBL8918884 | 0.82 | MAPK14 (0.51) | KMT2ACYP2C9CYP2C19MAPK14POLB | |
| Hydrochloric Acid SCHEMBL8921214 | 0.78 | CYP2C9 (0.43) | KMT2ACYP2C9CYP2C19MAPK14POLB | |
| SCHEMBL8917958 | 0.76 | ALDH1A1 (0.58) | POLBALDH1A1KDM4ELMNA | |
| SCHEMBL8919087 | 0.75 | DRD4 (0.42) | KMT2AL3MBTL1MEN1DRD4CHIA | |
| Oxalic Acid SCHEMBL7478101 | 0.75 | MEN1 (0.63) | KMT2ACYP2C19POLBGAAALDH1A1 | |
| SCHEMBL8920236 | 0.74 | DRD4 (0.41) | KMT2APOLBL3MBTL1MEN1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591751-A | CARBOSTYRIL DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-07 | — | — | US | claimed |
| EP-0636128-A1 | PIPERAZINOCARBONYLCARBOSTYRILS AS PERIPHERAL VASODILATORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-01 | — | — | EP | claimed |
| WO-1994019339-A1 | PIPERAZINOCARBONYLCARBOSTYRILS AS PERIPHERAL VASODILATORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-01 | — | — | WO | claimed |