Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.70 |
| ▸ | RECQL | P46063 | 1/20 | 0.70 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.65 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 2/20 | 0.51 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.51 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.51 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28564031 | 0.85 | TDP1 (0.63) | MEN1KMT2ALMNACYP3A4CYP2C19 | |
| SCHEMBL29367022 | 0.84 | PTPN7 (1.00) | MEN1KMT2ALMNAPTPN7TDP1 | |
| SCHEMBL25640 | 0.84 | PTPN7 (1.00) | MEN1KMT2ALMNAPTPN7TDP1 | |
| Naphthyloxyacetic Acid SCHEMBL27658809 | 0.83 | KDM4E (0.77) | MEN1KMT2ALMNACYP3A4CYP2C19 | |
| 1-Naphthol SCHEMBL9929466 | 0.83 | PTPN7 (0.74) | MEN1KMT2ALMNACYP3A4CYP2C19 | |
| SCHEMBL15201762 | 0.82 | PTPN7 (0.96) | MEN1KMT2ALMNAPTPN7TDP1 | |
| SCHEMBL15201765 | 0.82 | PTPN7 (0.96) | MEN1KMT2ALMNAPTPN7TDP1 | |
| Naphthalene SCHEMBL28768364 | 0.82 | TDP1 (0.96) | MEN1KMT2ALMNATDP1KDM4E | |
| Naphthyloxyacetic Acid SCHEMBL8920389 | 0.82 | ALDH1A1 (0.79) | MEN1KMT2ALMNATDP1MCL1 | |
| SCHEMBL29607554 | 0.81 | TDP1 (1.00) | MEN1KMT2ALMNATDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5631253-A | FUNGICIDES, INSECTICIDES AND MITICIDES USING METHYLOXIME PHENYLPROPENOIC ACID | ZENECA LIMITED (GB) | 1997-05-20 | — | — | US | disclosed |