1-Naphthol

1-Naphthol

SCHEMBL9929466

O=C(O)COc1ccc2ccccc2c1.Oc1cccc2ccccc12

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN7 P35236 1/20 0.74
MEN1 O00255 4/20 0.55
KMT2A Q03164 4/20 0.55
LMNA P02545 4/20 0.55
CYP3A4 P08684 1/20 0.55
CYP2C19 P33261 1/20 0.55
RECQL P46063 1/20 0.55
HPGD P15428 2/20 0.55
KDM4E B2RXH2 1/20 0.55
ALDH1A1 P00352 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
PPARG P37231 2/20 0.51
NCOA2 Q15596 2/20 0.51
NCOA1 Q15788 2/20 0.51
NCOA3 Q9Y6Q9 2/20 0.51
HTT P42858 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
NR2E3 Q9Y5X4 1/20 0.51
NCOR2 Q9Y618 1/20 0.51
MTNR1A P48039 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29367022 0.86 PTPN7 (1.00) PTPN7MEN1KMT2ALMNAHPGD
SCHEMBL25640 0.86 PTPN7 (1.00) PTPN7MEN1KMT2ALMNAHPGD
Naphthyloxyacetic Acid SCHEMBL27658809 0.86 KDM4E (0.77) PTPN7MEN1KMT2ALMNACYP3A4
SCHEMBL15201765 0.85 PTPN7 (0.96) PTPN7MEN1KMT2ALMNAHPGD
SCHEMBL15201762 0.85 PTPN7 (0.96) PTPN7MEN1KMT2ALMNAHPGD
SCHEMBL8920384 0.83 MEN1 (0.70) PTPN7MEN1KMT2ALMNACYP3A4
Ethylene Glycol SCHEMBL9493499 0.82 PTPN7 (0.90) PTPN7MEN1KMT2ALMNAHPGD
SCHEMBL10902015 0.81 PTPN7 (0.89) PTPN7MEN1KMT2ALMNAHPGD
Naphthyloxyacetic Acid SCHEMBL9929467 0.81 KDM4E (0.84) MEN1KMT2ALMNACYP3A4CYP2C19
SCHEMBL4076964 0.79 PTPN7 (0.85) PTPN7MEN1KMT2ALMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4059342-A1 METHODS FOR IMPROVING COMPETENCY OF PLANT CELLS Monsanto Technology LLC (US) 2022-09-21 EP disclosed
EP-3275308-B1 METHODS FOR IMPROVING COMPETENCY OF PLANT CELLS MONSANTO TECHNOLOGY LLC (US) 2022-05-11 EP disclosed
US-20210332375-A1 METHODS FOR IMPROVING COMPETENCY OF PLANT CELLS MONSANTO TECHNOLOGY LLC (US) 2021-10-28 US disclosed
US-10407685-B2 Methods for improving competency of plant cells MONSANTO TECHNOLOGY LLC (US) 2019-09-10 US disclosed
EP-3275308-A1 METHODS FOR IMPROVING COMPETENCY OF PLANT CELLS Monsanto Technology LLC (US) 2018-01-31 EP disclosed
EP-2651207-B1 METHODS FOR IMPROVING COMPETENCY OF PLANT CELLS MONSANTO TECHNOLOGY LLC (US) 2017-11-08 EP disclosed
US-20120156784-A1 Methods for Improving Competency of Plant Cells ADAMS JR WHITNEY R (US) 2012-06-21 US disclosed