Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8417805 | 0.89 | FDFT1 (0.35) | ALDH1A1LMNAHPGDHTTFDFT1 | |
| SCHEMBL8419863 | 0.85 | FDFT1 (0.34) | FDFT1KDM4E | |
| SCHEMBL8417907 | 0.84 | PHLPP2 (0.35) | ALDH1A1LMNAFDFT1KDM4E | |
| Hydrochloric Acid SCHEMBL8417982 | 0.83 | FDFT1 (0.41) | FDFT1 | |
| SCHEMBL8422019 | 0.81 | FDFT1 (0.36) | FDFT1 | |
| SCHEMBL8422049 | 0.80 | FDFT1 (0.40) | FDFT1 | |
| SCHEMBL8423271 | 0.79 | FDFT1 (0.38) | FDFT1 | |
| SCHEMBL8417909 | 0.79 | FDFT1 (0.38) | FDFT1 | |
| SCHEMBL8421874 | 0.79 | FDFT1 (0.39) | FDFT1 | |
| SCHEMBL8419759 | 0.79 | FDFT1 (0.44) | ALDH1A1LMNAFDFT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691349-A | ANTICHOLESTEROL AGENTS; ATHEROSCLEROSIS | ZENECA LIMITED (GB) | 1997-11-25 | — | — | US | disclosed |