Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 2/20 | 0.30 |
| ▸ | PLG | P00747 | 2/20 | 0.30 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.30 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8419593 | 0.88 | FDFT1 (0.49) | FDFT1MAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL8421874 | 0.86 | FDFT1 (0.39) | FDFT1 | |
| SCHEMBL8417632 | 0.86 | FDFT1 (0.60) | FDFT1 | |
| SCHEMBL8420062 | 0.85 | FDFT1 (0.47) | FDFT1 | |
| SCHEMBL8419673 | 0.85 | FDFT1 (0.41) | FDFT1 | |
| SCHEMBL8919905 | 0.84 | FDFT1 (0.41) | FDFT1MAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8419678 | 0.84 | FDFT1 (0.39) | FDFT1L3MBTL1MAPK1LMNAALDH1A1 | |
| SCHEMBL8422049 | 0.82 | FDFT1 (0.40) | FDFT1 | |
| SCHEMBL8420059 | 0.82 | FDFT1 (0.38) | FDFT1LMNACYP3A4F10PLG | |
| SCHEMBL8420031 | 0.81 | FDFT1 (0.42) | FDFT1LMNAALDH1A1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919793-A | QUINUCLIDINE DERIVATIVES, SQUALENE SYNTHETASE INHIBITORS, ANTICHOLESTEROL AGENTS | ZENECA LIMITED (GB) | 1999-07-06 | — | — | US | disclosed |