Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | RAD52 | P43351 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 2/20 | 0.34 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8919905 | 0.89 | FDFT1 (0.41) | POLBFDFT1ALDH1A1MAPK1RAB9A | |
| SCHEMBL8417805 | 0.87 | FDFT1 (0.35) | KDM4EFDFT1LMNAALDH1A1MAPT | |
| SCHEMBL8920428 | 0.84 | ALDH1A1 (0.36) | KDM4EFDFT1LMNAALDH1A1 | |
| SCHEMBL8419682 | 0.80 | FDFT1 (0.46) | KDM4EFDFT1LMNAALDH1A1 | |
| SCHEMBL8419678 | 0.80 | FDFT1 (0.39) | FDFT1LMNAALDH1A1MAPK1 | |
| SCHEMBL8918777 | 0.77 | TDP1 (0.37) | POLBFDFT1ALDH1A1MAPK1DRD3 | |
| SCHEMBL8419593 | 0.77 | FDFT1 (0.49) | POLBFDFT1ALDH1A1MAPK1MAPT | |
| SCHEMBL8968489 | 0.76 | FDFT1 (0.61) | FDFT1 | |
| SCHEMBL8421874 | 0.75 | FDFT1 (0.39) | FDFT1 | |
| SCHEMBL8419759 | 0.75 | FDFT1 (0.44) | FDFT1LMNAALDH1A1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919793-A | QUINUCLIDINE DERIVATIVES, SQUALENE SYNTHETASE INHIBITORS, ANTICHOLESTEROL AGENTS | ZENECA LIMITED (GB) | 1999-07-06 | — | — | US | disclosed |