Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.58 |
| ▸ | HPGD | P15428 | 6/20 | 0.58 |
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.47 |
| ▸ | TUBB | P07437 | 1/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30585651 | 0.87 | TUBB4A (0.50) | KDM4EHPGDHTTALDH1A1HSD17B10 | |
| SCHEMBL29065426 | 0.87 | TUBB4A (0.50) | KDM4EHPGDHTTALDH1A1HSD17B10 | |
| SCHEMBL153044 | 0.84 | KDM4E (0.65) | KDM4EHPGDHTTALDH1A1HSD17B10 | |
| SCHEMBL29629313 | 0.84 | HPGD (0.65) | KDM4EHPGDHTTALDH1A1HSD17B10 | |
| SCHEMBL29540056 | 0.84 | KDM4E (0.65) | KDM4EHPGDHTTALDH1A1HSD17B10 | |
| SCHEMBL29629312 | 0.84 | HPGD (0.65) | KDM4EHPGDHTTALDH1A1HSD17B10 | |
| SCHEMBL8922345 | 0.84 | HPGD (0.65) | KDM4EHPGDHTTALDH1A1HSD17B10 | |
| SCHEMBL11810127 | 0.83 | KDM4E (0.55) | KDM4EHPGDHTTALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL8920877 | 0.82 | HPGD (0.63) | KDM4EHPGDHTTALDH1A1HSD17B10 | |
| SCHEMBL13640231 | 0.81 | KDM4E (0.57) | KDM4EHPGDHTTALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670493-A | ANGIOGENESIS INHIBITORS | ADIR ET COMPAGNIE (FR) | 1997-09-23 | — | — | US | disclosed |
| US-4599399-A | Process for the preparation of poly[3,6-N-substituted carbazole-1,3,4-oxadiazole-2,5-diyl] from N-substituted carbazole-3,6-dicarboxylic acid | CHEVRON RESEARCH COMPANY (US) | 1986-07-08 | — | — | US | disclosed |
| US-3932456-A | VIRICIDES | RICHARDSON-MERRELL INC. (US) | 1976-01-13 | — | — | US | disclosed |