SCHEMBL13640231

SCHEMBL13640231

CCn1c2ccc(C(=O)C(=O)O)cc2c2cc(C(=O)C(=O)O)ccc21

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.57
ALDH1A1 P00352 5/20 0.57
HPGD P15428 4/20 0.57
TSHR P16473 2/20 0.57
HSD17B10 Q99714 2/20 0.57
HTT P42858 1/20 0.57
MAPT P10636 3/20 0.50
LMNA P02545 2/20 0.50
TUBB4A P04350 1/20 0.46
TUBB P07437 1/20 0.46
TUBA3C P0DPH7 1/20 0.46
TUBA1B P68363 1/20 0.46
TUBA4A P68366 1/20 0.46
TUBB4B P68371 1/20 0.46
TUBB3 Q13509 1/20 0.46
TUBB2A Q13885 1/20 0.46
TUBB8 Q3ZCM7 1/20 0.46
TUBA3E Q6PEY2 1/20 0.46
TUBA1A Q71U36 1/20 0.46
TUBA1C Q9BQE3 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6313847 0.92 KDM4E (0.62) KDM4EALDH1A1HPGDHSD17B10HTT
SCHEMBL29629312 0.86 HPGD (0.65) KDM4EALDH1A1HPGDTSHRHSD17B10
SCHEMBL29629313 0.86 HPGD (0.65) KDM4EALDH1A1HPGDTSHRHSD17B10
SCHEMBL8922345 0.86 HPGD (0.65) KDM4EALDH1A1HPGDTSHRHSD17B10
Hydrochloric Acid SCHEMBL8920877 0.84 HPGD (0.63) KDM4EALDH1A1HPGDTSHRHSD17B10
SCHEMBL29540056 0.82 KDM4E (0.65) KDM4EALDH1A1HPGDTSHRHSD17B10
SCHEMBL153044 0.82 KDM4E (0.65) KDM4EALDH1A1HPGDTSHRHSD17B10
SCHEMBL1979649 0.81 KDM4E (0.51) KDM4EALDH1A1HPGDTSHRHSD17B10
SCHEMBL8920858 0.81 KDM4E (0.58) KDM4EALDH1A1HPGDTSHRHSD17B10
SCHEMBL29849978 0.80 CNR2 (0.67) KDM4EALDH1A1HPGDTSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8957224-B2 Photoinitiators for UV-LED curable compositions and inks AGFA GRAPHICS NV (BE) 2015-02-17 US disclosed
US-8957224-B2 Photoinitiators for UV-LED curable compositions and inks AGFA GRAPHICS NV (BE) 2015-02-17 US disclosed
US-8569393-B2 UV-LED curable compositions and inks AGFA-GEVAERT N.V. (BE) 2013-10-29 US disclosed
US-8569393-B2 UV-LED curable compositions and inks AGFA-GEVAERT N.V. (BE) 2013-10-29 US disclosed
US-20120309861-A1 PHOTOINITIATORS FOR UV-LED CURABLE COMPOSITIONS AND INKS AGFA-GEVAERT N.V. (BE) 2012-12-06 US disclosed
US-20120309861-A1 PHOTOINITIATORS FOR UV-LED CURABLE COMPOSITIONS AND INKS AGFA-GEVAERT N.V. (BE) 2012-12-06 US disclosed
US-20120283349-A1 UV-LED CURABLE COMPOSITIONS AND INKS AGFA-GEVAERT N.V. (BE) 2012-11-08 US disclosed
US-20120283349-A1 UV-LED CURABLE COMPOSITIONS AND INKS AGFA-GEVAERT N.V. (BE) 2012-11-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120309861-A1 PHOTOINITIATORS FOR UV-LED CURABLE COMPOSITIONS AND INKS WEE1, CBX4, USP9X KDM4E 1156/4885ALDH1A1 1029/4885HPGD 3146/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.