Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 16/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 15/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 14/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 14/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 14/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 13/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 13/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 13/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 12/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 12/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 12/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.55 |
| ▸ | EGFR | P00533 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 1/20 | 0.51 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8921000 | 1.00 | HDAC1 (0.56) | HDAC1HDAC6HDAC11HDAC8HDAC2 | |
| SCHEMBL8921079 | 0.83 | ENPP2 (0.57) | HDAC1HDAC6HDAC11HDAC8HDAC2 | |
| SCHEMBL8920494 | 0.83 | ENPP2 (0.57) | HDAC1HDAC6HDAC11HDAC8HDAC2 | |
| SCHEMBL8922199 | 0.83 | ENPP2 (0.57) | HDAC1HDAC6HDAC11HDAC8HDAC2 | |
| SCHEMBL8921546 | 0.83 | ENPP2 (0.57) | HDAC1HDAC6HDAC11HDAC8HDAC2 | |
| SCHEMBL8920548 | 0.83 | ENPP2 (0.57) | HDAC1HDAC6HDAC11HDAC8HDAC2 | |
| SCHEMBL8921799 | 0.83 | ENPP2 (0.57) | HDAC1HDAC6HDAC11HDAC8HDAC2 | |
| SCHEMBL8921731 | 0.83 | ENPP2 (0.57) | HDAC1HDAC6HDAC11HDAC8HDAC2 | |
| SCHEMBL8920364 | 0.83 | ENPP2 (0.57) | HDAC1HDAC6HDAC11HDAC8HDAC2 | |
| SCHEMBL8920738 | 0.83 | ENPP2 (0.57) | HDAC1HDAC6HDAC11HDAC8HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670493-A | ANGIOGENESIS INHIBITORS | ADIR ET COMPAGNIE (FR) | 1997-09-23 | — | — | US | disclosed |