Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.30 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8923888 | 0.78 | SMN1; SMN2 (0.44) | DPP4NPC1HTTRAB9AL3MBTL1 | |
| SCHEMBL15635758 | 0.70 | GRIN2B (0.45) | DPP4GRIN2BGRIN2CHPGDKDM1A | |
| SCHEMBL11204598 | 0.64 | GRIN2B (0.46) | GRIN2BGRIN2CHPGDKDM1A | |
| SCHEMBL2738366 | 0.64 | HSD11B1 (0.45) | GPR119MAPTGRIN2BGRIN2CHPGD | |
| SCHEMBL30601931 | 0.64 | EPHX2 (0.43) | GPR119GRIN2BGRIN2CHPGDCHRM2 | |
| SCHEMBL23942574 | 0.64 | HSD11B1 (0.45) | GPR119MAPTGRIN2BGRIN2CHPGD | |
| SCHEMBL28735688 | 0.64 | CHRM2 (0.41) | GPR119HPGDCHRM2CHRM1CHRM3 | |
| SCHEMBL19312996 | 0.64 | HSD11B1 (0.45) | GPR119MAPTGRIN2BGRIN2CHPGD | |
| SCHEMBL18669890 | 0.64 | HSD11B1 (0.45) | GPR119MAPTGRIN2BGRIN2CHPGD | |
| SCHEMBL25347682 | 0.64 | CHRM2 (0.37) | GPR119MAPTHPGDCHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616573-A | Glucocorticoids | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-04-01 | — | — | US | disclosed |