Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | PREP | P48147 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8922565 | 0.84 | EPHX2 (0.37) | KMT2A | |
| SCHEMBL8696451 | 0.72 | SMN1; SMN2 (0.41) | SMN1; SMN2CYP2C19NPC1RAB9APREP | |
| SCHEMBL7443401 | 0.70 | SMN1; SMN2 (0.50) | SMN1; SMN2CYP2C19NPC1RAB9AHTR2C | |
| SCHEMBL4058433 | 0.70 | ALDH1A1 (0.50) | SMN1; SMN2CYP2C19NPC1RAB9AHTR2C | |
| SCHEMBL5980742 | 0.69 | FKBP1A (0.42) | SMN1; SMN2CYP2C19PREPDPP4KCNH2 | |
| SCHEMBL3710479 | 0.69 | SMN1; SMN2 (0.49) | SMN1; SMN2CYP2C19NPC1RAB9AHTR2C | |
| SCHEMBL6627044 | 0.69 | SMN1; SMN2 (0.50) | SMN1; SMN2CYP2C19NPC1RAB9AHTR2C | |
| SCHEMBL9237583 | 0.69 | DPP4 (0.43) | DPP4DPP7 | |
| SCHEMBL2135198 | 0.69 | ALDH1A1 (0.60) | CYP2C19KMT2AMEN1L3MBTL1 | |
| SCHEMBL313062 | 0.69 | ALDH1A1 (0.60) | CYP2C19KMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616573-A | Glucocorticoids | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-04-01 | — | — | US | disclosed |