Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | KDM6B | O15054 | 1/20 | 0.53 |
| ▸ | KDM5C | P41229 | 1/20 | 0.53 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.53 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.53 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.51 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.49 |
| ▸ | CA1 | P00915 | 4/20 | 0.49 |
| ▸ | CA2 | P00918 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | CA12 | O43570 | 3/20 | 0.49 |
| ▸ | CA7 | P43166 | 3/20 | 0.49 |
| ▸ | CA9 | Q16790 | 3/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.49 |
| ▸ | XDH | P47989 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6907035 | 0.93 | CA1 (0.55) | KDM4ETRPA1CA1CA2ALDH1A1 | |
| SCHEMBL8920996 | 0.93 | CA1 (0.55) | KDM4ETRPA1CA1CA2ALDH1A1 | |
| SCHEMBL6901141 | 0.85 | SRD5A2 (0.66) | KDM4ESRD5A2CA1CA2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8922281 | 0.83 | SRD5A2 (0.63) | KDM4ESRD5A2CA1CA2ALDH1A1 | |
| SCHEMBL17978157 | 0.80 | HSD17B1 (0.51) | KDM4ETRPA1CA1CA2ALDH1A1 | |
| SCHEMBL6907637 | 0.80 | SRD5A2 (0.76) | KDM4ESRD5A2ALDH1A1TSHRMAPT | |
| SCHEMBL13550865 | 0.79 | PTPRC (0.54) | KDM4ETRPA1CA1CA2ALDH1A1 | |
| SCHEMBL2000825 | 0.78 | KDM4E (0.67) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL29809867 | 0.78 | KDM4E (0.67) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL9644030 | 0.78 | CA1 (0.55) | KDM4ESRD5A2TRPA1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670493-A | ANGIOGENESIS INHIBITORS | ADIR ET COMPAGNIE (FR) | 1997-09-23 | — | — | US | disclosed |