Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 2/20 | 0.38 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 6/20 | 0.35 |
| ▸ | HTR1D | P28221 | 6/20 | 0.35 |
| ▸ | HTR1B | P28222 | 6/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8920374 | 0.96 | KMT2A (0.36) | PDK2PTPN1THRATHRBLMNA | |
| SCHEMBL8919249 | 0.92 | MEN1 (0.36) | PDK2LMNAHTR1AHTR1BCYP3A4 | |
| SCHEMBL8920315 | 0.91 | PDK2 (0.43) | PDK2NR5A1TSHRTHRATHRB | |
| SCHEMBL8918861 | 0.91 | PDK2 (0.43) | PDK2NR5A1TSHRTHRATHRB | |
| SCHEMBL8920583 | 0.87 | PDK2 (0.40) | PDK2THRATHRBPTPN11LMNA | |
| SCHEMBL8919289 | 0.87 | ALDH1A1 (0.39) | PDK2LMNAKDM4ECYP1A2CYP3A4 | |
| SCHEMBL8921438 | 0.85 | PDK2 (0.39) | PDK2NR5A1TSHRPTPN1THRA | |
| SCHEMBL8919076 | 0.82 | PDK2 (0.40) | PDK2HTR1AHTR1BMAPT | |
| SCHEMBL7827204 | 0.79 | PDK2 (0.42) | PDK2NR5A1TSHRPTPN1PTPN11 | |
| SCHEMBL7830530 | 0.79 | PDK2 (0.42) | PDK2NR5A1TSHRPTPN1PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691272-A | Carboxylate and heat-sensitive recording material using same | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5559247-A | Carboxylate and heat-sensitive recording material using same | MITSUI TOATSU CHEMICALS, INC. (JP) | 1996-09-24 | — | — | US | disclosed |
| EP-0679640-A1 | Carboxylate and heat-sensitive recording material using same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1995-11-02 | — | — | EP | disclosed |