SCHEMBL8919249

SCHEMBL8919249

CCCOc1ccc2c(c1)C(=N)NC21OC(C)O1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
PDK2 Q15119 1/20 0.35
C3AR1 Q16581 1/20 0.34
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA6 P23280 1/20 0.34
CA5A P35218 1/20 0.34
CA7 P43166 1/20 0.34
CA9 Q16790 1/20 0.34
CA14 Q9ULX7 1/20 0.34
CA5B Q9Y2D0 1/20 0.34
MAOA P21397 1/20 0.34
MAOB P27338 1/20 0.34
MAPT P10636 3/20 0.33
ALDH1A1 P00352 2/20 0.33
NQO2 P16083 1/20 0.33
MTNR1A P48039 1/20 0.33
MTNR1B P49286 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8920374 0.95 KMT2A (0.36) MEN1KMT2APDK2CA12CA1
SCHEMBL8921444 0.92 PDK2 (0.38) PDK2MAPTCYP3A4HTR1AHTR1B
SCHEMBL8919076 0.90 PDK2 (0.40) MEN1KMT2APDK2C3AR1CA12
SCHEMBL8919289 0.90 ALDH1A1 (0.39) MEN1KMT2APDK2CA12CA1
SCHEMBL8920583 0.85 PDK2 (0.40) MEN1KMT2APDK2CA12CA1
SCHEMBL8918904 0.83 ACHE (0.36) MEN1KMT2APDK2CA1CA2
SCHEMBL8918861 0.82 PDK2 (0.43) PDK2MAPTCYP3A4HTR1AHTR1B
SCHEMBL8920315 0.82 PDK2 (0.43) PDK2MAPTCYP3A4HTR1AHTR1B
SCHEMBL8917949 0.80 BRD4 (0.32) PDK2
SCHEMBL8918299 0.80 PDK2 (0.38) MEN1KMT2APDK2MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5691272-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1997-11-25 US disclosed
US-5559247-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1996-09-24 US disclosed
EP-0679640-A1 Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-11-02 EP disclosed