Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.45 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.41 |
| ▸ | MTOR | P42345 | 2/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5675180 | 0.88 | ALDH1A1 (0.62) | HPGDALDH1A1HSD17B10ALOX15MAPT | |
| SCHEMBL27395864 | 0.88 | ALDH1A1 (0.79) | HPGDALDH1A1HSD17B10ALOX15MAPT | |
| SCHEMBL8923331 | 0.88 | HPGD (0.56) | HPGDALDH1A1HSD17B10ALOX15MAPT | |
| SCHEMBL8921644 | 0.86 | ALDH1A1 (0.57) | HPGDALDH1A1HSD17B10ALOX15MAPT | |
| SCHEMBL9135743 | 0.86 | ALDH1A1 (0.63) | HPGDALDH1A1HSD17B10ALOX15HCRTR1 | |
| SCHEMBL9132104 | 0.85 | ALDH1A1 (0.65) | HPGDALDH1A1HSD17B10ALOX15HCRTR1 | |
| SCHEMBL9858082 | 0.83 | ALDH1A1 (0.48) | HPGDALDH1A1HSD17B10ALOX15HCRTR1 | |
| SCHEMBL9132101 | 0.81 | HPGD (0.57) | HPGDALDH1A1HSD17B10ALOX15SMN1; SMN2 | |
| SCHEMBL8923442 | 0.79 | ALDH1A1 (0.83) | HPGDALDH1A1HSD17B10ALOX15SMN1; SMN2 | |
| SCHEMBL8921416 | 0.79 | ALDH1A1 (0.59) | HPGDALDH1A1HSD17B10ALOX15MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684160-A | 3-aminopyrroles, methods for their synthesis and for their pharmaceutical use | ARZNEIMETTELWERK DRESDEN GMBH (DE) | 1997-11-04 | — | — | US | disclosed |
| US-5502051-A | CENTRAL NERVOUS SYSTEM, ANTISPASMODIC | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 1996-03-26 | — | — | US | disclosed |