Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.42 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.42 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.42 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.42 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.42 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.42 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.42 |
| ▸ | PRKDC | P78527 | 5/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | PHGDH | O43175 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8923331 | 0.89 | HPGD (0.56) | ALDH1A1HPGDALOX15HSD17B10PIK3CA | |
| SCHEMBL8922043 | 0.88 | ALDH1A1 (0.67) | ALDH1A1HPGDALOX15HSD17B10SMN1; SMN2 | |
| SCHEMBL8920563 | 0.88 | ALDH1A1 (0.70) | ALDH1A1HPGDALOX15HSD17B10SMN1; SMN2 | |
| SCHEMBL8923242 | 0.87 | ALDH1A1 (0.57) | ALDH1A1HPGDALOX15HSD17B10PIK3CA | |
| SCHEMBL8923375 | 0.87 | ALDH1A1 (0.63) | ALDH1A1HPGDALOX15HSD17B10PIK3CA | |
| SCHEMBL8922167 | 0.87 | HSD17B10 (0.57) | ALDH1A1HPGDALOX15HSD17B10SMN1; SMN2 | |
| SCHEMBL9132101 | 0.87 | HPGD (0.57) | ALDH1A1HPGDALOX15HSD17B10PIK3CA | |
| SCHEMBL8919988 | 0.87 | HPGD (0.42) | ALDH1A1HPGDALOX15HSD17B10SMN1; SMN2 | |
| SCHEMBL8921445 | 0.86 | HPGD (0.62) | ALDH1A1HPGDALOX15HSD17B10PIK3CA | |
| SCHEMBL9133737 | 0.85 | ALDH1A1 (0.41) | ALDH1A1HPGDALOX15HSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684160-A | 3-aminopyrroles, methods for their synthesis and for their pharmaceutical use | ARZNEIMETTELWERK DRESDEN GMBH (DE) | 1997-11-04 | — | — | US | claimed |
| US-5502051-A | CENTRAL NERVOUS SYSTEM, ANTISPASMODIC | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 1996-03-26 | — | — | US | claimed |
| US-5414082-A | Anticonvulsants | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 1995-05-09 | — | — | US | claimed |
| US-5684160-A | 3-aminopyrroles, methods for their synthesis and for their pharmaceutical use | ARZNEIMETTELWERK DRESDEN GMBH (DE) | 1997-11-04 | — | — | US | disclosed |
| US-5502051-A | CENTRAL NERVOUS SYSTEM, ANTISPASMODIC | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 1996-03-26 | — | — | US | disclosed |
| US-5414082-A | Anticonvulsants | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 1995-05-09 | — | — | US | disclosed |