Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.61 |
| ▸ | ALB | P02768 | 1/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.55 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8922627 | 1.00 | PPARA (0.61) | PPARAALBHRH3PLA2G4BKMT2A | |
| SCHEMBL28555169 | 1.00 | PPARA (0.61) | PPARAALBHRH3PLA2G4BKMT2A | |
| SCHEMBL6545281 | 1.00 | PPARA (0.61) | PPARAALBHRH3PLA2G4BKMT2A | |
| SCHEMBL28536384 | 0.98 | PPARA (0.63) | PPARAALBHRH3PLA2G4BKMT2A | |
| SCHEMBL120716 | 0.93 | KMT2A (0.58) | PPARAKMT2AMEN1L3MBTL1FFAR1 | |
| SCHEMBL8922076 | 0.91 | NR4A2 (0.61) | PPARAALBHRH3FFAR1 | |
| SCHEMBL31448424 | 0.91 | PPARA (0.71) | PPARAALBPLA2G4BL3MBTL1FFAR1 | |
| SCHEMBL29141429 | 0.91 | PPARA (0.71) | PPARAALBPLA2G4BL3MBTL1FFAR1 | |
| SCHEMBL21073528 | 0.91 | PPARA (0.71) | PPARAALBPLA2G4BL3MBTL1FFAR1 | |
| SCHEMBL31448470 | 0.89 | PPARA (0.73) | PPARAALBPLA2G4BL3MBTL1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112624997-A | Preparation method and application of 3-amino-2-oxazolidinone derivatives | 中国人民解放军军事科学院军事医学研究院 | 2021-04-09 | — | — | CN | disclosed |
| US-5679801-A | ANTIINFLAMMATORY AGENTS, ANTIASTHMATICS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-10-21 | — | — | US | disclosed |
| US-5242945-A | Antiinflammatory | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-09-07 | — | — | US | disclosed |
| EP-0508690-A1 | Tetronic and thiotetronic acid derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-10-14 | — | — | EP | disclosed |