Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.63 |
| ▸ | ALB | P02768 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.52 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8921579 | 0.98 | PPARA (0.61) | PPARAALBKMT2AMEN1L3MBTL1 | |
| SCHEMBL6545281 | 0.98 | PPARA (0.61) | PPARAALBKMT2AMEN1L3MBTL1 | |
| SCHEMBL28555169 | 0.98 | PPARA (0.61) | PPARAALBKMT2AMEN1L3MBTL1 | |
| SCHEMBL8922627 | 0.98 | PPARA (0.61) | PPARAALBKMT2AMEN1L3MBTL1 | |
| SCHEMBL120716 | 0.94 | KMT2A (0.58) | PPARAKMT2AMEN1L3MBTL1FFAR1 | |
| SCHEMBL31448470 | 0.90 | PPARA (0.73) | PPARAALBL3MBTL1FFAR1PLA2G4B | |
| SCHEMBL8922076 | 0.89 | NR4A2 (0.61) | PPARAALBFFAR1HRH3 | |
| SCHEMBL355627 | 0.89 | L3MBTL1 (0.67) | PPARAKMT2AMEN1L3MBTL1FFAR1 | |
| SCHEMBL31448424 | 0.88 | PPARA (0.71) | PPARAALBL3MBTL1FFAR1PLA2G4B | |
| SCHEMBL21073528 | 0.88 | PPARA (0.71) | PPARAALBL3MBTL1FFAR1PLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114149341-B | Aryloxy cyclohexyl amide AMPK agonist, and preparation method and medical application thereof | 中国药科大学 | 2023-07-21 | — | — | CN | disclosed |
| CN-114149341-A | Aryloxy cyclohexyl amide AMPK agonist and preparation method and medical application thereof | 中国药科大学 | 2022-03-08 | — | — | CN | disclosed |
| CN-112624997-A | Preparation method and application of 3-amino-2-oxazolidinone derivatives | 中国人民解放军军事科学院军事医学研究院 | 2021-04-09 | — | — | CN | disclosed |