Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.61 |
| ▸ | MAOB | P27338 | 3/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.54 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.54 |
| ▸ | ALB | P02768 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 2/20 | 0.52 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8921579 | 0.91 | PPARA (0.61) | FFAR1ALBPPARAHRH3 | |
| SCHEMBL6545281 | 0.91 | PPARA (0.61) | FFAR1ALBPPARAHRH3 | |
| SCHEMBL8922627 | 0.91 | PPARA (0.61) | FFAR1ALBPPARAHRH3 | |
| SCHEMBL28555169 | 0.91 | PPARA (0.61) | FFAR1ALBPPARAHRH3 | |
| SCHEMBL21991528 | 0.89 | NR4A2 (0.67) | NR4A2MAOBMAOAFFAR1FFAR4 | |
| SCHEMBL28536384 | 0.89 | PPARA (0.63) | FFAR1ALBPPARAHRH3 | |
| SCHEMBL1171526 | 0.86 | FFAR1 (0.67) | NR4A2FFAR1FFAR4ALBPPARA | |
| SCHEMBL1171933 | 0.86 | FFAR1 (0.67) | NR4A2FFAR1FFAR4ALBPPARA | |
| SCHEMBL1799635 | 0.86 | FFAR1 (0.67) | NR4A2FFAR1FFAR4ALBPPARA | |
| SCHEMBL1115038 | 0.84 | FFAR1 (0.69) | NR4A2FFAR1FFAR4PPARAALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5679801-A | ANTIINFLAMMATORY AGENTS, ANTIASTHMATICS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-10-21 | — | — | US | disclosed |
| US-5242945-A | Antiinflammatory | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-09-07 | — | — | US | disclosed |
| EP-0508690-A1 | Tetronic and thiotetronic acid derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-10-14 | — | — | EP | disclosed |