Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.41 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8921737 | 1.00 | CTSK (0.41) | CTSKAPPMAPTCYP1A2CYP2C9 | |
| SCHEMBL8921588 | 1.00 | CTSK (0.41) | CTSKAPPMAPTCYP1A2CYP2C9 | |
| SCHEMBL8921748 | 1.00 | CTSK (0.41) | CTSKAPPMAPTCYP1A2CYP2C9 | |
| SCHEMBL8920849 | 0.94 | APP (0.39) | CTSKAPPMAPTMEN1KMT2A | |
| SCHEMBL8921535 | 0.94 | APP (0.39) | CTSKAPPMAPTMEN1KMT2A | |
| SCHEMBL8920834 | 0.94 | APP (0.39) | CTSKAPPMAPTMEN1KMT2A | |
| SCHEMBL8921550 | 0.94 | APP (0.39) | CTSKAPPMAPTMEN1KMT2A | |
| SCHEMBL8921553 | 0.94 | APP (0.39) | CTSKAPPMAPTMEN1KMT2A | |
| SCHEMBL8923113 | 0.92 | APP (0.37) | CTSKAPPMAPTMEN1KMT2A | |
| SCHEMBL8921779 | 0.92 | APP (0.37) | CTSKAPPMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5637613-A | ANTITUMOR AGENT; IMMUNOSUPPRESSANTS | FOURNIER INDUSTRIE ET SANTE (FR) | 1997-06-10 | — | — | US | disclosed |