Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.45 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.42 |
| ▸ | ITGAV | P06756 | 3/20 | 0.42 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TPH1 | P17752 | 2/20 | 0.40 |
| ▸ | TPH2 | Q8IWU9 | 2/20 | 0.40 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7413312 | 0.89 | MME (0.45) | MMEITGB3ITGAVGPR34 | |
| SCHEMBL7419794 | 0.83 | MME (0.50) | MMEPTGDRITGB3ITGAVGPR34 | |
| SCHEMBL8923043 | 0.83 | ITGA4 (0.51) | — | |
| SCHEMBL8924951 | 0.82 | KDM4E (0.38) | MMEPTPN1 | |
| SCHEMBL8924880 | 0.82 | KDM4E (0.38) | MMEPTPN1 | |
| SCHEMBL8923729 | 0.82 | PDCD1 (0.42) | POLBKMT2A | |
| SCHEMBL7417475 | 0.82 | MME (0.53) | MMEPTGDRITGB3ITGAVFFAR1 | |
| SCHEMBL7417467 | 0.82 | MME (0.53) | MMEPTGDRITGB3ITGAVFFAR1 | |
| SCHEMBL7411130 | 0.81 | ITGA4 (0.42) | MMEKMT2A | |
| SCHEMBL7415659 | 0.80 | KMT2A (0.48) | MMEPTGDRPOLBGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0660840-B1 | PHOSPHONO SUBSTITUTED TETRAZOLE DERIVATIVES | CIBA GEIGY AG (CH) | 1997-05-07 | — | — | EP | disclosed |
| WO-1996026729-A1 | PHOSPHONO SUBSTITUTED TETRAZOLE DERIVATIVES AS ECE INHIBITORS | CIBA-GEIGY AG (CH) | 1996-09-06 | — | — | WO | disclosed |
| US-5550119-A | ENDOTHELIN-CONVERTING ENZYM INHIBITORS | CIBA-GEIGY CORPORATION (US) | 1996-08-27 | — | — | US | disclosed |
| EP-0660840-A1 | PHOSPHONO SUBSTITUTED TETRAZOLE DERIVATIVES. | CIBA GEIGY AG (CH) | 1995-07-05 | — | — | EP | disclosed |
| WO-1994005677-A1 | PHOSPHONO SUBSTITUTED TETRAZOLE DERIVATIVES | CIBA-GEIGY AG (CH) | 1994-03-17 | — | — | WO | disclosed |