SCHEMBL8921684

SCHEMBL8921684

CCC1CCC(C2CCC(C3(c4ccc(F)c(F)c4)CCCCC3)CC2)CC1

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 14/20 0.50
SLC6A4 P31645 13/20 0.50
SLC6A2 P23975 10/20 0.50
CYP2D6 P10635 2/20 0.34
KCNH2 Q12809 2/20 0.34
CYP1A1 P04798 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2C19 P33261 1/20 0.34
OPRM1 P35372 1/20 0.32
OPRD1 P41143 1/20 0.32
OPRK1 P41145 1/20 0.32
PGR P06401 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7760357 0.96 SLC6A3 (0.53) SLC6A3SLC6A4SLC6A2CYP2D6KCNH2
SCHEMBL8921676 0.91 SLC6A4 (0.49) SLC6A3SLC6A4SLC6A2CYP2D6KCNH2
SCHEMBL8921677 0.91 SLC6A4 (0.49) SLC6A3SLC6A4SLC6A2CYP2D6KCNH2
SCHEMBL8921688 0.91 SLC6A4 (0.49) SLC6A3SLC6A4SLC6A2CYP2D6KCNH2
SCHEMBL6524970 0.86 SLC6A4 (0.51) SLC6A3SLC6A4SLC6A2CYP2D6KCNH2
SCHEMBL8020936 0.82 SLC6A4 (0.48) SLC6A3SLC6A4SLC6A2CYP2D6KCNH2
SCHEMBL8536568 0.82 SLC6A4 (0.48) SLC6A3SLC6A4SLC6A2CYP2D6KCNH2
SCHEMBL10778007 0.81 SLC6A4 (0.46) SLC6A3SLC6A4SLC6A2CYP2D6KCNH2
SCHEMBL28624808 0.80 SLC6A4 (0.67) SLC6A3SLC6A4SLC6A2CYP2D6KCNH2
Ethylene SCHEMBL28629416 0.78 SLC6A4 (0.63) SLC6A3SLC6A4SLC6A2CYP2D6KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5595686-A Silacyclohexane compounds, a liquid crystal composition comprising the same and a liquid crystal device comprising the composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 1997-01-21 US disclosed