SCHEMBL8536568

SCHEMBL8536568

CCCCC[C@H]1CC[C@H](C2(c3ccc(F)c(F)c3)CCCCC2)CC1

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 12/20 0.48
SLC6A3 Q01959 12/20 0.48
SLC6A2 P23975 10/20 0.48
CYP1A2 P05177 2/20 0.37
CYP2D6 P10635 3/20 0.33
KCNH2 Q12809 2/20 0.33
CYP2C19 P33261 2/20 0.33
CYP1A1 P04798 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
OPRL1 P41146 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C8 P10632 1/20 0.32
CYP2C9 P11712 1/20 0.32
S1PR3 Q99500 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8020936 1.00 SLC6A4 (0.48) SLC6A4SLC6A3SLC6A2CYP1A2CYP2D6
SCHEMBL6524970 0.91 SLC6A4 (0.51) SLC6A4SLC6A3SLC6A2CYP1A2CYP2D6
SCHEMBL8536712 0.88 CYP1A2 (0.36) SLC6A4SLC6A3SLC6A2CYP1A2CYP2D6
SCHEMBL8536711 0.88 CYP1A2 (0.36) SLC6A4SLC6A3SLC6A2CYP1A2CYP2D6
SCHEMBL9180980 0.86 SLC6A3 (0.40) SLC6A4SLC6A3SLC6A2CYP1A2KCNH2
SCHEMBL7760357 0.86 SLC6A3 (0.53) SLC6A4SLC6A3SLC6A2CYP1A2CYP2D6
SCHEMBL10778007 0.86 SLC6A4 (0.46) SLC6A4SLC6A3SLC6A2CYP1A2CYP2D6
SCHEMBL6524968 0.84 SLC6A4 (0.51) SLC6A4SLC6A3SLC6A2CYP1A2CYP2D6
SCHEMBL8921684 0.82 SLC6A3 (0.50) SLC6A4SLC6A3SLC6A2CYP1A2CYP2D6
SCHEMBL10652906 0.81 CYP1A2 (0.40) CYP1A2CYP2D6CYP2C19CYP3A4CYP2C8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5762826-A Liquid crystal composition and a liquid crystal display element which contains it SHIN-ETSU CHEMICAL CO., LTD. (JP) 1998-06-09 US disclosed