SCHEMBL8921697

SCHEMBL8921697

CCCC(=O)OCC(C)(C)COC(=O)CCC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.50
DGKA P23743 1/20 0.40
LMNA P02545 2/20 0.38
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
HSD17B10 Q99714 1/20 0.38
SERPINE1 P05121 1/20 0.37
P2RY10 O00398 1/20 0.36
GPR34 Q9UPC5 1/20 0.36
PAM P19021 2/20 0.36
FFAR3 O14843 3/20 0.36
HDAC3 O15379 3/20 0.36
HDAC1 Q13547 3/20 0.36
HDAC2 Q92769 3/20 0.36
HDAC8 Q9BY41 3/20 0.36
CYP1A2 P05177 1/20 0.35
TSHR P16473 2/20 0.35
MAPT P10636 1/20 0.34
ADRA2A P08913 1/20 0.33
ADRA1A P35348 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17718078 0.92 ALDH1A1 (0.43) ALDH1A1DGKALMNACES2CES1
SCHEMBL4452697 0.88 ALDH1A1 (0.40) ALDH1A1DGKALMNAHSD17B10SERPINE1
SCHEMBL6406466 0.86 DGKA (0.52) ALDH1A1DGKALMNACES2CES1
SCHEMBL517466 0.86 ALDH1A1 (0.50) ALDH1A1DGKALMNACES2CES1
SCHEMBL3203892 0.86 ALDH1A1 (0.50) ALDH1A1DGKALMNACES2CES1
SCHEMBL855142 0.85 DGKA (0.61) ALDH1A1DGKALMNAP2RY10GPR34
SCHEMBL9323708 0.84 ALDH1A1 (0.48) ALDH1A1DGKALMNACES2CES1
SCHEMBL525482 0.83 ALDH1A1 (0.52) ALDH1A1DGKALMNACES2CES1
SCHEMBL33575 0.83 DGKA (0.64) ALDH1A1DGKALMNAP2RY10GPR34
SCHEMBL17812465 0.83 DGKA (0.64) ALDH1A1DGKALMNAP2RY10GPR34

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-9125080-A None JP disclosed
JP-9125085-A None JP disclosed
US-10793807-B2 Organoleptic compounds INTERNATIONAL FLAVORS & FRAGRANCES INC (US) 2020-10-06 US disclosed
WO-2020018737-A1 NOVEL ORGANOLEPTIC COMPOUNDS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2020-01-23 WO disclosed
JP-H09125080-A HEAT-RESISTANT LUBRICATING OIL COMPOSITION TONEN CORP 1997-05-13 JP disclosed
JP-H09125085-A HEAT-RESISTANT LUBRICATING OIL COMPOSITION TONEN CORP 1997-05-13 JP disclosed