Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 7/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.59 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.59 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.59 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | CLK2 | P49760 | 1/20 | 0.55 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | TOP2A | P11388 | 5/20 | 0.52 |
| ▸ | TOP2B | Q02880 | 5/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10856738 | 0.99 | KCNH2 (0.65) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL10529369 | 0.92 | KCNH2 (0.65) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| Pd-117558 SCHEMBL8922444 | 0.92 | KCNH2 (0.65) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| Hydrochloric Acid SCHEMBL10529374 | 0.91 | ALDH1A1 (0.70) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| Pd-117558 SCHEMBL10529381 | 0.91 | KCNH2 (0.64) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL9373032 | 0.90 | KCNH2 (0.81) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL10401506 | 0.90 | KCNH2 (0.61) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL10764195 | 0.90 | KCNH2 (0.63) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL9379634 | 0.90 | KCNH2 (0.63) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL10692692 | 0.90 | KCNH2 (0.65) | KCNH2ALDH1A1POLBOPRM1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0236673-B1 | Process for quinoline-3-carboxylic acid antibacterial agents | WARNER LAMBERT CO (US) | 1994-07-13 | — | — | EP | claimed |
| EP-0235589-B1 | USE OF QUINOLONE AND NAPHTHYRIDINE ANTIBIOTICS FOR THE MANUFACTURE OF OPHTHALMIC MEDICAMENTS | WARNER-LAMBERT COMPANY (US) | 1992-10-28 | — | — | EP | claimed |
| EP-0198678-B1 | A PROCESS FOR PREPARING SUBSTITUTED QUINOLINE-3-CARBOXYLIC ACIDS | WARNER-LAMBERT COMPANY (US) | 1991-08-21 | — | — | EP | claimed |
| EP-0200307-B1 | IMPROVED PROCESS FOR PRODUCTION OF QUINOLINE-3-CARBOXYLIC ACID ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1989-12-20 | — | — | EP | claimed |
| US-4772706-A | Process for quinoline-3-carboxylic acid antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1988-09-20 | — | — | US | claimed |
| EP-0236673-A2 | Process for quinoline-3-carboxylic acid antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1987-09-16 | — | — | EP | claimed |
| EP-0235589-A2 | Use of quinolone and naphthyridine antibiotics for the manufacture of ophthalmic medicaments | WARNER-LAMBERT COMPANY (US) | 1987-09-09 | — | — | EP | claimed |
| US-4665079-A | QUINOLINE DERIVATIVES | WARNER-LAMBERT COMPANY (US) | 1987-05-12 | — | — | US | claimed |
| EP-0198678-A2 | A process for preparing substituted quinoline-3-carboxylic acids | WARNER-LAMBERT COMPANY (US) | 1986-10-22 | — | — | EP | claimed |
| US-4578473-A | Process for quinoline-3-carboxylic acid antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1986-03-25 | — | — | US | claimed |
| EP-0153163-A2 | 7-Substituted-1-cyclopropyl-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids; 7-substituted-1-cyclopropyl-1,4-dihydro-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acids; their derivatives; and a process for preparing the compounds | WARNER-LAMBERT COMPANY (US) | 1985-08-28 | — | — | EP | claimed |
| US-5672600-A | Antimicrobial dithiocarbamoyl quinolones | THE PROCTER & GAMBLE COMPANY (US) | 1997-09-30 | — | — | US | disclosed |
| US-5387748-A | Antimicrobial dithiocarbamoyl quinolones | PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) | 1995-02-07 | — | — | US | disclosed |
| EP-0236673-B1 | Process for quinoline-3-carboxylic acid antibacterial agents | WARNER LAMBERT CO (US) | 1994-07-13 | — | — | EP | disclosed |
| EP-0207420-B1 | PYRIDONECARBOXYLIC ACID DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1992-05-06 | — | — | EP | disclosed |
| US-4638067-A | NAPHTHYRIDINE AND QUINOLINE CARBOXYLIC ACIDS | WARNER-LAMBERT CO. (US) | 1987-01-20 | — | — | US | disclosed |
| EP-0200307-A1 | Improved process for production of quinoline-3-carboxylic acid antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1986-11-05 | — | — | EP | disclosed |
| EP-0198678-A2 | A process for preparing substituted quinoline-3-carboxylic acids | WARNER-LAMBERT COMPANY (US) | 1986-10-22 | — | — | EP | disclosed |
| US-4578473-A | Process for quinoline-3-carboxylic acid antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1986-03-25 | — | — | US | disclosed |
| EP-0153163-A2 | 7-Substituted-1-cyclopropyl-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids; 7-substituted-1-cyclopropyl-1,4-dihydro-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acids; their derivatives; and a process for preparing the compounds | WARNER-LAMBERT COMPANY (US) | 1985-08-28 | — | — | EP | disclosed |