SCHEMBL8922144

SCHEMBL8922144

Cc1ccc(C(C)C)c(OCCN(C)Cc2c(C)c(O)c(C)c(C)c2OCCO)c1

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ADRA1D P25100 1/20 0.61
ADRA1A P35348 1/20 0.61
ADRA1B P35368 1/20 0.61
ALDH1A1 P00352 5/20 0.50
KDM4E B2RXH2 2/20 0.50
TDP1 Q9NUW8 1/20 0.50
KMT2A Q03164 4/20 0.48
ATM Q13315 4/20 0.48
MAPT P10636 1/20 0.48
MAPK1 P28482 1/20 0.48
SMN1; SMN2 Q16637 2/20 0.45
NPBWR1 P48145 1/20 0.45
MCHR1 Q99705 1/20 0.45
MEN1 O00255 3/20 0.40
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
ADRB2 P07550 1/20 0.37
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8923620 0.90 ADRA1D (0.74) ADRA1DADRA1AADRA1BALDH1A1KDM4E
SCHEMBL8925987 0.86 ADRA1D (0.81) ADRA1DADRA1AADRA1BALDH1A1KDM4E
Hydrochloric Acid SCHEMBL8924680 0.85 ADRA1D (0.80) ADRA1DADRA1AADRA1BALDH1A1KDM4E
SCHEMBL8924282 0.78 ADRA1D (0.58) ADRA1DADRA1AADRA1BALDH1A1KDM4E
SCHEMBL8924208 0.78 ADRA1D (0.81) ADRA1DADRA1AADRA1BALDH1A1KDM4E
SCHEMBL8923225 0.78 ADRA1D (0.85) ADRA1DADRA1AADRA1BALDH1A1KDM4E
SCHEMBL8922600 0.78 ADRA1D (0.57) ADRA1DADRA1AADRA1BALDH1A1KDM4E
SCHEMBL8925084 0.77 ADRA1D (0.80) ADRA1DADRA1AADRA1BALDH1A1KDM4E
SCHEMBL8923592 0.77 ADRA1D (0.83) ADRA1DADRA1AADRA1BALDH1A1KDM4E
Hydrochloric Acid SCHEMBL8924390 0.77 ADRA1D (0.83) ADRA1DADRA1AADRA1BALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5624961-A Benzylaminoethoxybenzene derivatives, production thereof and use thereof JAPAN TOBACCO INC. (JP) 1997-04-29 US disclosed
EP-0693474-A1 NOVEL BENZYLAMINOETHOXYBENZENE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF Toyo Boseki Kabushiki Kaisha (JP) 1996-01-24 EP disclosed