Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | ATM | Q13315 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8922600 | 0.91 | ADRA1D (0.57) | ADRA1DADRA1AADRA1BALDH1A1KDM4E | |
| SCHEMBL8923620 | 0.88 | ADRA1D (0.74) | ADRA1DADRA1AADRA1BALDH1A1KDM4E | |
| SCHEMBL8923441 | 0.88 | KMT2A (0.56) | ADRA1DADRA1AADRA1BALDH1A1KDM4E | |
| SCHEMBL8924712 | 0.82 | ADRA1D (0.51) | ADRA1DADRA1AADRA1BALDH1A1KDM4E | |
| SCHEMBL8924115 | 0.79 | ALDH1A1 (0.54) | ADRA1DADRA1AADRA1BALDH1A1KDM4E | |
| SCHEMBL8922559 | 0.79 | ADRA1D (0.70) | ADRA1DADRA1AADRA1BALDH1A1KDM4E | |
| SCHEMBL8922144 | 0.78 | ADRA1D (0.61) | ADRA1DADRA1AADRA1BALDH1A1KDM4E | |
| SCHEMBL8925966 | 0.77 | ADRA1D (0.68) | ADRA1DADRA1AADRA1BALDH1A1KDM4E | |
| SCHEMBL8922909 | 0.77 | ADRA1D (0.88) | ADRA1DADRA1AADRA1BALDH1A1KDM4E | |
| SCHEMBL8922883 | 0.77 | ADRA1D (0.56) | ADRA1DADRA1AADRA1BALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624961-A | Benzylaminoethoxybenzene derivatives, production thereof and use thereof | JAPAN TOBACCO INC. (JP) | 1997-04-29 | — | — | US | disclosed |
| EP-0693474-A1 | NOVEL BENZYLAMINOETHOXYBENZENE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Toyo Boseki Kabushiki Kaisha (JP) | 1996-01-24 | — | — | EP | disclosed |