Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 4/20 | 0.44 |
| ▸ | RXRB | P28702 | 4/20 | 0.44 |
| ▸ | RXRG | P48443 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | PPOX | P50336 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.40 |
| ▸ | RHEB | Q15382 | 1/20 | 0.40 |
| ▸ | CFD | P00746 | 1/20 | 0.40 |
| ▸ | ESRRA | P11474 | 1/20 | 0.39 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.39 |
| ▸ | PARG | Q86W56 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8924039 | 0.84 | POLB (0.46) | RXRARXRBRXRGTDP1KDM4E | |
| SCHEMBL940864 | 0.82 | RXRB (0.54) | RXRARXRBRXRGKMT2AKDM4E | |
| SCHEMBL31000476 | 0.82 | RXRB (0.54) | RXRARXRBRXRGKMT2AKDM4E | |
| SCHEMBL29962914 | 0.81 | RHEB (0.39) | MEN1TTRPPOXKMT2ATDP1 | |
| SCHEMBL8921521 | 0.81 | NR1H2 (0.48) | TDP1KDM4EPOLBAR | |
| SCHEMBL29962860 | 0.80 | MEN1 (0.43) | MEN1TTRPPOXKMT2ATDP1 | |
| SCHEMBL9151921 | 0.80 | MEN1 (0.43) | MEN1TTRPPOXKMT2ATDP1 | |
| SCHEMBL9150725 | 0.80 | EGLN1 (0.41) | MEN1TTRPPOXKMT2ATDP1 | |
| SCHEMBL695791 | 0.78 | POLB (0.54) | MEN1KMT2ATDP1POLBCYP2C19 | |
| SCHEMBL9847753 | 0.78 | RARB (0.51) | RXRBTDP1KDM4EPOLBIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670084-A | Alignment layer material for liquid crystal display devices | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-09-23 | — | — | US | disclosed |
| EP-0708149-A1 | Alignment layer material for liquid crystal display devices | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-04-24 | — | — | EP | disclosed |