Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 4/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | GALK1 | P51570 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | PLEC | Q15149 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 2/20 | 0.42 |
| ▸ | RXRB | P28702 | 2/20 | 0.42 |
| ▸ | AR | P10275 | 2/20 | 0.41 |
| ▸ | DHODH | Q02127 | 2/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL695791 | 0.90 | POLB (0.54) | POLBTDP1MCL1DHODHL3MBTL1 | |
| SCHEMBL8978047 | 0.89 | POLB (0.45) | POLBAKR1C2AKR1C1XDHCES2 | |
| SCHEMBL29093106 | 0.87 | AR (0.56) | POLBAKR1C2XDHTDP1AR | |
| SCHEMBL8921521 | 0.86 | NR1H2 (0.48) | POLBAKR1C2AKR1C1XDHTDP1 | |
| SCHEMBL22528190 | 0.85 | POLB (0.50) | POLBAKR1C2AKR1C1TDP1GALK1 | |
| SCHEMBL8922330 | 0.84 | RXRA (0.44) | POLBCES2TDP1RXRARXRB | |
| SCHEMBL9251468 | 0.84 | AKR1C2 (0.40) | POLBAKR1C2AKR1C1XDHTDP1 | |
| SCHEMBL29962299 | 0.84 | AKR1C2 (0.40) | POLBAKR1C2AKR1C1XDHTDP1 | |
| SCHEMBL4410053 | 0.81 | POLB (0.51) | POLBAKR1C2TDP1GALK1CASP6 | |
| SCHEMBL278193 | 0.80 | POLB (0.67) | POLBXDHTDP1GALK1CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670084-A | Alignment layer material for liquid crystal display devices | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-09-23 | — | — | US | disclosed |
| EP-0708149-A1 | Alignment layer material for liquid crystal display devices | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-04-24 | — | — | EP | disclosed |