Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1539862 | 0.94 | MAPT (0.48) | SMN1; SMN2MAPTL3MBTL1NPC1RAB9A | |
| SCHEMBL3268751 | 0.86 | MAPT (0.49) | SMN1; SMN2MAPTL3MBTL1NPC1RAB9A | |
| SCHEMBL16062042 | 0.81 | NPC1 (0.46) | SMN1; SMN2MAPTL3MBTL1NPC1RAB9A | |
| SCHEMBL24968079 | 0.79 | L3MBTL1 (0.63) | SMN1; SMN2MAPTL3MBTL1RAB9AMAPK1 | |
| SCHEMBL3410825 | 0.78 | L3MBTL1 (0.44) | SMN1; SMN2MAPTL3MBTL1MAPK1TDP1 | |
| SCHEMBL31643406 | 0.77 | LMNA (0.51) | MAPTRAB9AMAPK1TDP1MEN1 | |
| SCHEMBL7786636 | 0.75 | PTPN1 (0.49) | SMN1; SMN2MAPTL3MBTL1NPC1RAB9A | |
| SCHEMBL30301550 | 0.75 | LMNA (0.49) | SMN1; SMN2MAPTL3MBTL1NPC1RAB9A | |
| SCHEMBL26974234 | 0.75 | LMNA (0.36) | SMN1; SMN2LMNAKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL30958004 | 0.74 | LMNA (0.48) | SMN1; SMN2MAPTL3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624961-A | Benzylaminoethoxybenzene derivatives, production thereof and use thereof | JAPAN TOBACCO INC. (JP) | 1997-04-29 | — | — | US | disclosed |
| EP-0693474-A1 | NOVEL BENZYLAMINOETHOXYBENZENE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Toyo Boseki Kabushiki Kaisha (JP) | 1996-01-24 | — | — | EP | disclosed |